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The contents on our website are for informational purposes only, and are not intended to diagnose any medical condition, replace the advice of a healthcare professional, or provide any medical device, diagnosis, or treatment. Use only as directed. Consult your healthcare provider before using supplements or providing supplements to children under the age of 18. The information provided herein is intended for your general knowledge only and is not intended to be, nor is it, medical advice or a substitute for medical advice. If you have or suspect you have a specific medical condition or disease, please consult your healthcare provider.

The testimonials on our site are individual experiences and do not guarantee that you will achieve the same results. Weight loss outcomes mentioned in testimonials are not typical and may vary from person to person. These testimonials are voluntarily provided and are not paid for or offered in exchange for free products.

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  2. Harvie MN, Pegington M, Mattson MP, et al. The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women. Int J Obes. 2011;35(5):714-727. https://pubmed.ncbi.nlm.nih.gov/20921964/
  3. Patterson RE, Laughlin GA, LaCroix AZ, et al. Intermittent Fasting and Human Metabolic Health. J Acad Nutr Diet. 2015;115(8):1203-1212. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516560/
  4. Anton SD, Moehl K, Donahoo WT, et al. Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting. Obesity. 2018;26(2):254-268. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/
  5. Longo VD, Mattson MP. Fasting: Molecular Mechanisms and Clinical Applications. Cell Metab. 2014;19(2):181-192. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946160/
  6. Chaix A, Zarrinpar A, Miu P, Panda S. Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges. Cell Metab. 2014;20(6):991-1005. https://pubmed.ncbi.nlm.nih.gov/25470547/
  7. Stote KS, Baer DJ, Spears K, et al. A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am J Clin Nutr. 2007;85(4):981-988. https://pubmed.ncbi.nlm.nih.gov/17413096/
  8. Tinsley GM, La Bounty PM. Effects of intermittent fasting on body composition and clinical health markers in humans. Nutr Rev. 2015;73(10):661-674. https://pubmed.ncbi.nlm.nih.gov/26374764/
  9. Hatori M, Vollmers C, Zarrinpar A, et al. Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet. Cell Metab. 2012;15(6):848-860. https://pubmed.ncbi.nlm.nih.gov/22608008/
  10. Gabel K, et al. “Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults.” Nutrition and Healthy Aging. https://pubmed.ncbi.nlm.nih.gov/29951594/
  11. Longo VD, Panda S. “Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan.” Cell Metabolism. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388543/
  12. Megalli, S., et al. “Gynostemma pentaphyllum decreases feeding behavior and body weight via modulating food intake regulatory peptides in high-fat-diet fed rats.” Journal of Functional Foods, 2015.
  13. Huyen, V. T. T., et al. “Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients.” Evidence-Based Complementary and Alternative Medicine, 2012.
  14. Park SH, Huh TL, Kim SY, et al.”Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial” https://pubmed.ncbi.nlm.nih.gov/23804546/
  15. Frédéric N Daussin, Elsa Heyman, Yan Burelle, et al. “Effects of (−)-epicatechin on mitochondria” Nutrition Reviews, Volume 79, Issue 1, January 2021, Pages 25–41, https://doi.org/10.1093/nutrit/nuaa094
  16. “Effects of Epicatechin on Molecular Modulators of Skeletal Muscle Growth and Differentiation,” The Journal of Nutritional Biochemistry, 2014. Available at: https://pubmed.ncbi.nlm.nih.gov/24314870/
  17. Yu Y et al. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 adn AMPK/Sirt1 signaling in mice. https://doi.org/10.1038/srep03142
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